Anti -TRPV4 Rabbit pAb

價格：在線咨詢

貨號：

DRF101231

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	TRPV4 rabbit polyclonal
Protein full name	Transient receptor potential cation channel subfamily V member 4
Synonyms	TrpV4, Osm-9-like TRP channel 4, OTRPC4, Transient receptor potential protein 12, TRP12, Vanilloid receptor-like protein 2, VR-OAC
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse TRPV4
Isotype	IgG
Purity	Affinity purification
Predicted MW.	98 kDa
Observed MW.	98 kDa
Uniprot ID	Q9EPK8

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse	1: 500-1: 1000	heart

Background

TRPV4 is a cation-selective channel, activated in response to systemic osmotic pressure. FUNCTION: Non-selective calcium permanent cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. SUBUNIT, Interacts with calmodulin. Interacts with Map7 and Src family Tyr protein kinases LYN, SRC, FYN, HCK, LCK and YES.

Images

Western blot analysis of TRPV4 (GB111107) at dilution of 1: 1000

Lane 1: Mouse heart tissue lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.

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