Anti -Fas Ligand Rabbit pAb

價格：在線咨詢

貨號：

DRF101622

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	Fas Ligand rabbit polyclonal
Protein full name	Tumor necrosis factor ligand superfamily member 6
Synonyms	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6, TNLG1A, Fas ligand
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse FASL
Isotype	IgG
Purity	Affinity purification
Predicted MW.	31KDa
Observed MW.	31KDa
Uniprot ID	P48023,P41047,P36940

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1:500-1:1000	LNCap,breast cancer,liver,spleen,brain

Background

Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells . Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development . Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis.Tumor necrosis factor ligand superfamily member 6, soluble form: Induces FAS-mediated activation of NF-kappa-B, initiating non-apoptotic signaling pathways . Can induce apoptosis but does not appear to be essential for this process.

Images

Western blot analysis of FASL(GB11090) at dilution of 1:1000.

Lane 1:LNCaP cell tissue lysate

Lane 2:Human breast cancer tissue lysate

Lane 3:Mouse liver tissue lysate

Lane 4:Mouse spleen tissue lysate

Lane 5:Mouse brain tissue lysate

Lane 6:Rat liver tissue lysate

Lane 7:Rat spleen tissue lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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