Anti -TNF-α Rabbit pAb

價格：在線咨詢

貨號：

DRF101674

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	TNF-α rabbit polyclonal
Protein full name	Tumor necrosis factor alpha
Synonyms	TNF,DIF,TNF-alpha,TNFA,TNFSF2,Tumour necrosis factor, Tumour necrosis factor alpha, TNF-α, tumor necrosis factor, TNLG1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse TNF-α
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane, Secreted
Predicted MW.	26 kDa
Observed MW.	26 kDa
Uniprot ID	P01375, P06804

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 200-1: 500	lymph node, thymus, spleen, lung
IHC	Mouse	1: 400-1: 1000	lung, septic lung, hepatitis
IF	Mouse	1: 300-1: 800	lung

Background

Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.

Images

	Western blot analysis of TNF-α (GB11188) at dilution of 1: 500
	Western blot analysis of TNF-α (GB11188) at dilution of 1: 500
	Immunohistochemistry analysis of paraffin-embedded mouse lung using TNF-α(GB11188)at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse septic lung using TNF-α(GB11188)at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse hepatitis using TNF-α(GB11188)at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed mouse lung using TNF-α(GB11188)at dilution of 1: 400

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

Publications:

	Title	Journal	Pubmed ID	Application
1	Early Enteral Nutrition Preserves Intestinal Barrier Function through Reducing the Formation of Neutrophil Extracellular Traps (NETs) in Critically Ill Surgical Patients.	Oxidative Medicine and Cellular Longevity	33294125	IHC
2	QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism.	Cell Death & Disease	32382069	IHC
3	Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases.	Nature Communications	31040273	WB
4	Induction of pathological changes and impaired expression of cytokines in developing female rat spleen after chronic excess fluoride exposure.	Toxicology and Industrial Health	30463494	IHC

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