CXCL13 is a small chemokine belonging to the CXC chemokine family. this chemokine is selectively chemotactic for B cells belonging to both the B-1 and B-2 subsets, and elicits its effects by interacting with chemokine receptor CXCR5. CXCL13 and its receptor CXCR5 control the organization of B cells within follicles of lymphoid tissues. In T lymphocytes, CXCL13 expression is thought to reflect a germinal center origin of the T cell, particularly a subset of T cells called follicular B helper T cells (or TFH cells). Hence, expression of CXCL13 in T-cell lymphomas, such as Angioimmunoblastic T-cell Lymphoma, is thought to reflect a germinal center origin of the neoplastic T-cells.
Images
Immunohistochemistry analysis of paraffin-embedded mouse spleen using
BCA1 (GB11919) at dilution of 1: 2000
Immunohistochemistry analysis of paraffin-embedded mouse brain using
BCA1 (GB11919) at dilution of 1: 2000
Immunohistochemistry analysis of paraffin-embedded rat cerebellum using
BCA1 (GB11919) at dilution of 1: 2000
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .