The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.
Images
Western blot analysis of CCR7 (GB11503) at dilution of 1:800.
Lane 1:Jukat cell lysate
Lane 2:THP-1 cell lysate
Lane 3:Raw264.7 cell lysate
Lane 4:Mouse Inflammatory spleen tissue lysate
Lane 5:Mouse Inflammatory liver tissue lysate
Lane 6:Mouse thymus tissue lysate
Lane 7:Rat Inflammatory spleen tissue lysate
Lane 8:Rat Inflammatory liver tissue lysate
Lane 9:Rat thymus tissue lysate
Western blot analysis of preincubated with the control peptide antigen (left) and CCR7 (GB11503) at dilution of 1:800(right).
Lane 1:Jurkat cell lysate
Lane 2:THP-1 cell lysate
Lane 3:Mouse thymus tissue lysate
Lane 4:Rat thymus tissue lysate
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .