Anti -LEF1 Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

DRF101949

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	LEF1 rabbit polyclonal
Protein full name	Lymphoid enhancer-binding factor 1
Synonyms	LEF-1, Lef1, TCF1 alpha, TCF1ALPHA, TCF7L3, FLJ46390, TCF10, LEF1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse LEF1
Isotype	IgG
Purity	Affinity purification
Subcellular location	Nucleus
Uniprot ID	P27782, Q9QXN1

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Mouse, Rat	1: 900-1: 1800	thymus
IF	Mouse, Rat	1: 600-1: 1200	thymus, spleen

Background

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

Images

	Immunohistochemistry analysis of paraffin-embedded mouse thymus using LEF1 (GB111887) at dilution of 1: 1800
	Immunohistochemistry analysis of paraffin-embedded rat thymus using LEF1 (GB111887) at dilution of 1: 1800
	Immunofluorescent analysis of paraformaldehyde-fixed mouse spleen using LEF1 (GB111887) at dilution of 1: 1200
	Immunofluorescent analysis of paraformaldehyde-fixed mouse thymus using LEF1 (GB111887) at dilution of 1: 1200
	Immunofluorescent analysis of paraformaldehyde-fixed rat thymus using LEF1 (GB111887) at dilution of 1: 1200

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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