Anti -FCGRT/FCRN Rabbit pAb

價格：在線咨詢

貨號：

DRF101954

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	FCGRT/FCRN rabbit polyclonal
Protein full name	IgG receptor FcRn large subunit p51
Synonyms	FcRn, IgG Fc fragment receptor transporter alpha chain, Neonatal Fc receptor, Fcgrt
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse FCGRT
Isotype	IgG
Purity	Affinity purification
Predicted MW.	40 kDa
Observed MW.	40 kDa

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse	1: 500-1: 1000	liver, kidney, small intestine

Background

FcRN present in the intestinal epithelium of neonatal mice and rats mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn animals to acquire passive immunity. FcRn (also designated FCGRT, Brambell receptor, FcRn ? chain, IgG Gc receptor and neonatal Fc-receptor) is comprised of a heavy chain and ∫-2-Microglobulin. FcRn heavy chain shows approximately 35% amino acid identity to an MHC class I molecule. FcRN localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal catabolism. This protection mechanism is a major constituent for ensuring IgG are the longest lived of all plasma proteins.

Images

圖片 1.png

Western blot analysis of FCRN (GB112081)

at dilution of 1: 1000

Lane 1: Mouse liver tissue lysate

Lane 2: Mouse kidney tissue lysate

Lane 3: Mouse small intestine tissue lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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