Anti -Neurofilament heavy polypeptide Mouse mAb

價格：在線咨詢

貨號：

KT011610

產品規(guī)格：

100ul

Applications：

IHC

Species：

品牌：

萬物

購買數量：

立即詢價在線咨詢 400-1016-218

產品詳情操作說明注意事項

Product Information

Description	Neurofilament heavy polypeptide mouse monoclonal
Protein full name	Neurofilament heavy polypeptide
Synonyms	NF-H, 200 kDa neurofilament protein, Neurofilament triplet H protein, Nefh, Kiaa0845, Nfh, NF200, NF
Immunogen	Recombinant protein corresponding to Mouse NF200
Isotype	IgG1
Purity	Affinity purification
Subcellular location	Cytoplasm
Uniprot ID	P19246

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Mouse	1: 2000-1: 4000	brain, cerebellum

Background

NEFH (NF200), also named as KIAA0845 and NFH, belongs to the intermediate filament family. It has an important function in mature axons that is not subserved by the two smaller NF proteins. Neurofilaments are the 10 nm intermediate filaments found specifically in neurons. They are a major component of the cell's cytoskeleton, and provide support for normal axonal radial growth. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The names given to the three major neurofilament subunits are based upon the apparent molecular weight of the mammalian subunits on SDS-PAGE: NF-L, 65-68 kDa; NF-M,145-160 kDa and NF-H, 200-220 kDa. This antibody can recognize both NEFH and NEFM.

Images

Immunohistochemistry analysis of paraffin-embedded mouse brain using

NF200 (GB12143) at dilution of 1: 4000

Immunohistochemistry analysis of paraffin-embedded mouse brain using

NF200 (GB12143) at dilution of 1: 4000

Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using NF200 (GB12143) at dilution of 1: 4000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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