Anti -Ki67 Rabbit pAb

價(jià)格：在線咨詢

貨號：

KT011685

產(chǎn)品規(guī)格：

Applications：

Species：

H,M

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	Ki67 rabbit polyclonal antibody
Protein full name	Proliferation marker protein Ki-67
Synonyms	MKI67, marker of proliferation Ki-67, KIA, MIB-, MIB-1, PPP1R105
Immunogen	Recombinant protein corresponding to Mouse Ki67
Isotype	IgG
Subcellular location	Nucleus,nucleolus
Purity	Affinity purification
Predicted MW.	359KDa
Observed MW.	359KDa
Uniprot ID	E9PVX6

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse	1:300-1:600	liver, stomach, colon

Background

Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (By similarity).

Images

Picture 1.png

Western blot analysis of KI67 (GB11030) at dilution of 1: 300

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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