Anti -GAD65 Mouse mAb

價(jià)格：在線咨詢

貨號：

KT011779

產(chǎn)品規(guī)格：

100 μL

Applications：

WB/IHC/IF

Species：

H/M/R,M/R,M/R

品牌：

萬物

購買數(shù)量：

立即詢價(jià) 在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	GAD65 mouse monoclonal antibody
Protein full name	Glutamate decarboxylase 2
Synonyms	GAD2, GAD65, glutamate decarboxylase 2, 65 kDa glutamic acid decarboxylase, DCE 2, Glutamic Acid Decarboxylase 2; Glutamic Acid Decarboxylase 65
Immunogen	Recombinant protein corresponding to Mouse GAD65
Isotype	IgG
Purity	Affinity purification
Predicted MW.	65 kDa
Observed MW.	65 kDa
Uniprot ID	Q05329, Q05683, P48320

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse, Rat	1:500-1:1000	brain, cerebral cortex, hippocampus, cerebellum
IHC/IF	Mouse, Rat	1:500-1:2000	brain, cerebellum, epencephalon

Background

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Images

	Western blot analysis of GAD65 (GB12562) at dilution of 1: 1000
	Immunohistochemistry of paraffin embedded mouse cerebellum using GAD65 (GB12562) at dilution of (300x lens)
	Immunohistochemistry analysis of paraffin-embedded mouse brain using GAD65 (GB12562) at dilution of 1: 1000(350x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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