Anti -Gemin 2 Rabbit pAb

價格：在線咨詢

貨號：

KT011794

產品規(guī)格：

100ul

Applications：

WB/IHC/IF

Species：

H/M/R,M/R,M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產品詳情操作說明注意事項

Product Information

Description	Gemin 2 rabbit polyclonal
Protein full name	Gem-associated protein 2
Synonyms	Gemin2, GEMIN2, SIP1, SIP1-delta, Survival of motor neuron protein-interacting protein 1, gem nuclear organelle associated protein 2
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse Gemin 2
Isotype	IgG
Purity	Affinity purification
Subcellular location	Nucleus
Predicted MW.	30 kDa
Observed MW.	30 kDa
Uniprot ID	O14893, Q9CQQ4

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	muscle, testis
IHC	Mouse, Rat	1: 1000-1: 2000	lung, testis, bone, spinal cord
IF	Mouse, Rat	1: 500-1: 1000	lung, testis, bone, spinal cord

Background

This gene encodes one of the proteins found in the SMN complex, which consists of several gemini proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.

Images

	Western blot analysis of Gemin 2 (GB11862) at dilution of 1: 1000 Lane 1: HepG2 cell lysate Lane 2: 293T cell lysate Lane 3: Jurkat cell lysate Lane 4: HeLa cell lysate Lane 5: NIH/3T3 cell lysate Lane 6: Mouse muscle tissue lysate Lane 7: Rat muscle tissue lysate Lane 8: Rat testis tissue lysate
	Immunohistochemistry analysis of paraffin-embedded rat lung using Gemin 2 (GB11862) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse testis using Gemin 2 (GB11862) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat testis using Gemin 2 (GB11862) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse bone using Gemin 2 (GB11862) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat spinal cord using Gemin 2 (GB11862) at dilution of 1: 1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.

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