Anti -ADAMTS1 Rabbit pAb

價格：在線咨詢

貨號：

KT011923

產品規(guī)格：

100 μL

Applications：

Species：

M,R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產品詳情操作說明注意事項

Product Information

Description	ADAMTS1 rabbit polyclonal antibody
Protein full name	A disintegrin and metalloproteinase with thrombospondin motifs 1
Synonyms	ADAMTS1, ADAMTS, METH1. KIAA1346, A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 1, ADAM metallopeptidase with thrombospondin type 1 motif 1
Immunogen	KLH conjugated Synthetic peptide corresponding to Human ADAMTS1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	106 kDa
Observed MW.	110 kDa
Uniprot ID	P97857, Q9WUQ1

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse, Rat	1: 500-1: 1000	heart, brain

Background

ADAMTS1 (a disintegrin and metalloproteinase with thrombospondin motifs 1), is the founding member of the family of secreted zinc proteases with a multidomain structure. The protein precursor consists of a signal peptide and the following domains: pro, catalytic, disintegrinlike, TS type 1 motif, cysteine rich, spacer and a variable number of thrombospondin type 1 motifs. Based on their substrate specificity, ADAMTS1 and associated family members may be key enzymes in the degradation of cartilage leading to inflammation and arthritis. It is an active protease cleaving alpha 2 macroglobulin, aggrecan and versican. ADAMTS1 is essential for normal growth and the structure and function of the kidneys, adrenal glands and female reproductive organs. It also plays an important role in atherosclerosis.

Images

Western blot analysis of ADAMTS1 (GB111011) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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