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Anti -MCU Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT011933
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
HM
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information

Description

MCU rabbit polyclonal antibody

Protein full name

Calcium uniporter protein, mitochondrial

Synonyms

HsMCU, Coiled-coil domain-containing protein 109A, MCU, C10orf42, CCDC109A

Immunogen

Recombinant protein corresponding to Mouse MCU

Isotype

IgG

Purity

Affinity purification

Predicted MW.

40 kDa

Observed MW.

30-35 kDa

Uniprot ID

Q8NE86, Q3UMR5





Applications

Applications

Species

Dilution

Positive Sample

WB

Human, Mouse

1: 500-1: 800

PANC-1, A549, NIH/3T3





Background

MCU, also known as CCDC109A, is a mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes the pore-forming and calcium-conducting subunit of the uniporter complex (uniplex) . The MCU protein is composed of two coiled-coil domains, two TMDs, and a short motif of amino acids between the two TMDs. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways. Involved in buffering the amplitude of systolic calcium rises in cardiomyocytes.





Images

Picture 1.png

Western blot analysis of MCU (GB111353) at dilution of 1: 500





Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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