Anti -FOXO4/AFX Rabbit pAb

價格：在線咨詢

貨號：

KT011965

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

H,R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	FOXO4 rabbit polyclonal antibody
Protein full name	Forkhead box protein O4
Synonyms	Fork head domain transcription factor AFX1, FOXO4, AFX, AFX1, MLLT7
Immunogen	Recombinant protein corresponding to Human FOXO4
Isotype	IgG
Purity	Affinity purification
Predicted MW.	54 kDa
Observed MW.	54 kDa
Uniprot ID	P98177, D4A433

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Rat	1: 500-1: 1000	293T, MDA-MB-231, Jurkat

Background

FOXO4, also named as AFX, AFX1 and MLLT7, is a transcription factor which involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1.FOXO down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias.

Images

Picture 1.png

Western blot analysis of FOXO4 (GB111173) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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