Anti -PFKL Rabbit pAb

價格：在線咨詢

貨號：

KT011973

產品規(guī)格：

100 μL

Applications：

IHC

Species：

品牌：

萬物

購買數(shù)量：

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產品詳情操作說明注意事項

Product Information

Description	PFKL rabbit polyclonal antibody
Protein full name	ATP-dependent 6-phosphofructokinase, liver type
Synonyms	ATP-PFK, PFK-L, PFK-B, PFKL, 6-phosphofructokinase type B, Phosphofructo-1-kinase isozyme B
Immunogen	Recombinant protein corresponding to Human PFKL
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm
Uniprot ID	P17858

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Human	1: 1000-1: 3000	hepatocarcinoma, liver, prostate

Background

PFKL is the Liver isozyme of PFK (Phosphofructokinase), which is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate by ATP. Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway.

Images

	Immunohistochemistry of paraffin embedded human hepatocarcinoma using pfk1 (GB111136) at dilution of 1:1600 (400x lens)
	Immunohistochemistry of paraffin embedded human liver using pfk1 (GB111136) at dilution of 1:1600 (400x lens)
	Immunohistochemistry of paraffin embedded human prostate using pfk1 (GB111136) at dilution of 1:1600 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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