The
product of this gene phosphorylates the beta-2-adrenergic receptor and
appears to mediate agonist-specific desensitization observed at high
agonist concentrations. This protein is an ubiquitous cytosolic enzyme
that specifically phosphorylates the activated form of the
beta-adrenergic and related G-protein-coupled receptors. Abnormal
coupling of beta-adrenergic receptor to G protein is involved in the
pathogenesis of the failing heart.
Images
Western blot analysis of grk2 (GB111115) at dilution of 1: 500
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .