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Anti -Myoglobin Rabbit pAb

價格: 在線咨詢
貨號:
KT012039
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
MR
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

Myoglobin rabbit polyclonal antibody

Protein full name

Myoglobin

Synonyms

Mb, MB, PVALB, myoglobgin, myoglobin, Myoglobin

Immunogen

Recombinant protein corresponding to Human Myoglobin

Isotype

IgG

Purity

Affinity purification

Predicted MW.

17 kDa

Observed MW.

17 kDa

Uniprot ID

P04247, Q9QZ76




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

heart, skeletal muscle




Background


Myoglobin is a small heme containing protein responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.




Images


Western blot analysis of Myoglobin (GB111170) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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