Ctsd, CatD, CD, CLN10, CPSD, Epididymis secretory sperm binding protein Li 130P, HEL S 130P, Lysosomal aspartyl peptidase
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Cathepsin D
Isotype
IgG
Purity
Affinity purification
Subcellular location
Lysosome, Secreted
Uniprot ID
P07339, P18242
Applications
Applications
Species
Dilution
Positive Sample
IHC/IF
Mouse
1: 200-1: 400
liver
Background
CTSD(Cathepsin D) is also named as CPSD,belongs to the peptidase A1 family.It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. The prepro-CTSD isoform has a molecular mass of 52 kDa, the pro-CTSD 48 kDa and the mature CTSD 32 kDa. It is a lysosomal acid protease found in neutrophils and monocytes and involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.Defects in CTSD are the cause of neuronal ceroid lipofuscinosis type 10 (CLN10).This antibody is specific to CTSD.
Images
Immunofluorescence of paraffin embedded mouse liver using cathepsinD (GB111861) at dilution of 1:200 (260x lens)
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer
PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).