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Anti -YTHDF1 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT012078
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
MR
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

YTHDF1 rabbit polyclonal antibody

Protein full name

YTH domain-containing family protein 1

Synonyms

Dermatomyositis associated with cancer putative autoantigen 1 homolog, DACA-1 homolog, Ythdf1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse YTHDF1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm

Uniprot ID

P59326




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Mouse, Rat

1: 500-1: 1000

brain




Background


YTHDF1, also named as YTH domain-containing family protein 1 or C20orf21. YTHDF1 specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. YTHDF1 acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation.




Images


Picture 1.png

Immunohistochemistry of paraffin embedded mouse brain using YTHDF1 (GB111390) at dilution of 1:500 (400x lens)


Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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