Anti -YTHDF1 Rabbit pAb

價格：在線咨詢

貨號：

KT012078

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC/IF

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	YTHDF1 rabbit polyclonal antibody
Protein full name	YTH domain-containing family protein 1
Synonyms	Dermatomyositis associated with cancer putative autoantigen 1 homolog, DACA-1 homolog, Ythdf1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse YTHDF1
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm
Uniprot ID	P59326

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Mouse, Rat	1: 500-1: 1000	brain

Background

YTHDF1, also named as YTH domain-containing family protein 1 or C20orf21. YTHDF1 specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. YTHDF1 acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation.

Images

Picture 1.png

Immunohistochemistry of paraffin embedded mouse brain using YTHDF1 (GB111390) at dilution of 1:500 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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