Anti -SIK1 Rabbit pAb

價(jià)格：在線咨詢

貨號：

KT012132

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

M,R

品牌：

萬物

購買數(shù)量：

立即詢價(jià) 在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	SIK1 rabbit polyclonal antibody
Protein full name	Serine/threonine-protein kinase SIK1
Synonyms	HRT-20, Myocardial SNF1-like kinase, Serine/threonine-protein kinase SNF1-like kinase 1, Salt-inducible kinase 1, SIK1
Immunogen	Recombinant protein corresponding to Mouse SIK1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	85 kDa
Observed MW.	90 kDa
Uniprot ID	Q60670, Q9R1U5

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse, Rat	1: 500-1: 1000	stomach, lung, ovary, heart

Background

SIK1(Salt-inducible kinase 1) is also named as SIK, SNF1LK and belongs to the CAMK Ser/Thr protein kinase family. It associates constitutively with the NK regulatory complex and is responsible for increases in its catalytic activity following small elevations in intracellular sodium concentrations. SIK1 is required for phosphorylation of class II HDACs and for expression of MEF2 target genes in myocytes. Defects in SIK1 may be associated with some cancers, such as breast cancers. Loss of SIK1 correlates with poor patient outcome in breast cancers.

Images

Picture 1.png

Western blot analysis of Msk (GB111034) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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