c fos serum response element binding factor, SRF, ERP, MCM1, SAP2
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse SRF
Isotype
IgG
Purity
Affinity purification
Subcellular location
Nucleus
Uniprot ID
P11831, Q9JM73, D3ZHH8
Applications
Applications
Species
Dilution
Positive Sample
IHC/IF
Human, Mouse, Rat
1: 500-1: 3000
breast cancer, colon, heart, lung, lung cancer, ovarian cancer, prostate, small intestine, stomach, subcutaneous transplant tumor
Background
This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens and SRF) box super family of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation.
Images
Immunohistochemistry of paraffin embedded human breast cancer using SRF (GB111048) at dilution of 1:1500 (400x lens)
Immunohistochemistry of paraffin embedded human lung cancer using SRF (GB111048) at dilution of 1:1500 (400x lens)
Immunohistochemistry of paraffin embedded human ovarian cancer using SRF (GB111048) at dilution of 1:1500 (400x lens)
Immunohistochemistry of paraffin embedded human stomach using SRF (GB111048) at dilution of 1:1500 (400x lens)
Immunohistochemistry of paraffin embedded human subcutaneous transplant tumor using SRF (GB111048) at dilution of 1:1500 (400x lens)
Immunohistochemistry of paraffin embedded mouse heart using SRF (GB111048) at dilution of 1:1500 (400x lens)
Immunohistochemistry of paraffin embedded mouse lung using SRF (GB111048) at dilution of 1:1500 (400x lens)
Immunohistochemistry of paraffin embedded mouse small intestine using SRF (GB111048) at dilution of 1:1500 (400x lens)
Immunofluorescence of paraffin embedded human breast cancer using SRF (GB111048) at dilution of 1:800 (400x lens)
Immunofluorescence of paraffin embedded human prostate using SRF (GB111048) at dilution of 1:800 (400x lens)
Immunofluorescence of paraffin embedded mouse heart using SRF (GB111048) at dilution of 1:800 (400x lens)
Immunofluorescence of paraffin embedded mouse small intestine using SRF (GB111048) at dilution of 1:800 (400x lens)
Immunofluorescence of paraffin embedded rat colon using SRF (GB111048) at dilution of 1:800 (400x lens)
Immunofluorescence of paraffin embedded rat lung using SRF (GB111048) at dilution of 1:800 (400x lens)
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).