Anti -RB-1 Rabbit pAb

價格：在線咨詢

貨號：

KT012142

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC/IF

Species：

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	RB-1 rabbit polyclonal antibody
Protein full name	Retinoblastoma-associated protein
Synonyms	pRb, Rb, pp105, Rb1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse RB-1
Isotype	IgG
Purity	Affinity purification
Subcellular location	Nucleus
Uniprot ID	P13405, P33568

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Mouse, Rat	1: 500-1: 2500	brain, kidney, lung, Skeletal muscle

Background

RB1 belongs to the retinoblastoma protein family. It is a key regulator of entry into cell division that acts as a tumor suppressor. RB1 acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. It is directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation.

Images

	Immunohistochemistry of paraffin embedded mouse brain using RB1 (GB111111) at dilution of 1:700 (400x lens)
	Immunohistochemistry of paraffin embedded mouse kidney using RB1 (GB111111) at dilution of 1:700 (400x lens)
	Immunohistochemistry of paraffin embedded mouse Skeletal muscle using RB1 (GB111111) at dilution of 1:1400 (400x lens)
	Immunohistochemistry of paraffin embedded rat brain using RB1 (GB111111) at dilution of 1:1400 (400x lens)
	Immunohistochemistry of paraffin embedded rat brain using RB1 (GB111111) at dilution of 1:700 (400x lens)
	Immunohistochemistry of paraffin embedded rat kidney using RB1 (GB111111) at dilution of 1:1400 (400x lens)
	Immunohistochemistry of paraffin embedded rat lung using RB1 (GB111111) at dilution of 1:700 (400x lens)
	Immunofluorescence of paraffin embedded mouse Brain using RB1 (GB111111) at dilution of 1:1400 (400x lens)
	Immunofluorescence of paraffin embedded mouse Skeletal muscle using RB1 (GB111111) at dilution of 1:1400 (400x lens)
	Immunofluorescence of paraffin embedded rat brain using RB1 (GB111111) at dilution of 1:1400 (400x lens)
	Immunofluorescence of paraffin embedded rat kidney using RB1 (GB111111) at dilution of 1:1400 (400x lens)
	Immunofluorescence of paraffin embedded rat lung using RB1 (GB111111) at dilution of 1:1400 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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