Anti -Raptor Rabbit pAb

價格：在線咨詢

貨號：

KT012206

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	Raptor rabbit polyclonal antibody
Protein full name	Regulatory-associated protein of mTOR
Synonyms	RPTOR, KOG1, Mip1, regulatory associated protein of MTOR complex 1, KIAA1303, P150 target of rapamycin (TOR)-scaffold protein
Immunogen	Recombinant protein corresponding to Mouse Raptor
Isotype	IgG
Purity	Affinity purification
Predicted MW.	73 kDa
Observed MW.	73 kDa
Uniprot ID	Q8K4Q0, Q8N122

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse	1: 500-1: 1000	lung, colon, brain

Background

Regulatory-associated protein of mTOR also known as raptor or KIAA1303 is an adapter protein that is encoded in humans by the RPTOR gene. RPTOR encodes part of a signaling pathway regulating cell growth which responds to nutrient and insulin levels. RPTOR is an evolutionarily conserved protein with multiple roles in the mTOR pathway. The adapter protein and mTOR kinase form a stoichiometric complex. The encoded protein also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. It upregulates S6 kinase, the downstream effector ribosomal protein, and it downregulates the mTOR kinase. RPTOR also has a positive role in maintaining cell size and mTOR protein expression. The association of mTOR and RPTOR is stabilized by nutrient deprivation and other conditions which suppress the mTOR pathway.

Images

Western blot analysis of Raptor (GB11590) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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