KLH conjugated Synthetic peptide corresponding to human NF-κB p65 around the phosphorylation site of Serine 536
Isotype
IgG
Purity
Affinity purification
Predicted MW.
65 kDa
Observed MW.
65KDa
Uniprot ID
Q04206,Q04207
Applications
Applications
Species
Dilution
Positive Sample
WB
Human, Mouse, Rat
1: 600-1: 1000
lung, spleen, liver
Background
NF-kappa-B
is a pleiotropic transcription factor present in almost all cell types
and is the endpoint of a series of signal transduction events that are
initiated by a vast array of stimuli related to many biological
processes such as inflammation, immunity, differentiation, cell growth,
tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric
complex formed by the Rel-like domain-containing proteins RELA/p65,
RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric
p65-p50 complex appears to be most abundant one. The dimers bind at
kappa-B sites in the DNA of their target genes and the individual dimers
have distinct preferences for different kappa-B sites that they can
bind with distinguishable affinity and specificity.
Images
Western blot analysis of P-NFkBp65 (GB11142-1) at dilution of 1: 600
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).