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Anti -Rab5 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT012276
產(chǎn)品規(guī)格:
100 μL
Applications:
WB/IHC/IF
Species:
H/M/R,H,H
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

Rab5 rabbit polyclonal antibody

Protein full name

Ras-related protein Rab-5A

Synonyms

Rab5a, NnyRab5a, Ubiquitin-protein ligase D3

Immunogen

KLH conjugated Synthetic peptide corresponding to Human Rab5

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Cell membrane

Predicted MW.

24 kDa

Observed MW.

24 kDa

Uniprot ID

P20339, Q9CQD1





Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1000

brain, testis

IHC/IF

Human

1: 500-1: 2000

lung, lung cancer





Background


Rab5 is a 24 kDa GTP-binding protein that regulates the fusion of plasma membrane -derived clathrin-coated vesicles with early endosomes, and homotypic fusion among early endosomes1. Localized to the cytoplasmic side of the plasma membrane, clathrin -coated vesicles and early endosomes, Rab5 appears to regulate vesicle fusion through a cycle of GDP/GTP e xchange and GTP hydrolysis. The different guanine nucleotide binding states of Rab5 may affect its ability to associate or dissociate with membranes during endocytotic membrane traffic. 




Images


Picture 1.png

Western blot analysis of RAB5A (GB111104) at dilution of 1: 500

Picture 2.png

Immunohistochemistry of paraffin embedded human lung cancer using RAB5A (GB111104) at dilution of 1: 1000 (400x lens)

Picture 3.png

Immunohistochemistry of paraffin embedded human lung using RAB5A (GB111104) at dilution of 1: 1000 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
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