KLH conjugated Synthetic peptide corresponding to Mouse GSK3 alpha
Isotype
IgG
Purity
Affinity purification
Subcellular location
Cytoplasm, Nucleus
Uniprot ID
Q2NL51, P18265
Applications
Applications
Species
Dilution
Positive Sample
IHC/IF
Mouse, Rat
1: 500-1: 3000
colon, epencephalon, heart, small intestine, spleen, thymus, brain
Background
Glycogen synthase kinase 3 alpha belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily; GSK3 subsubfamily. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, myb, and the transcription factor c jun. GSK3 phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK3 and subsequently inhibits GSK3 acutely leading to the stimulation of glycogen synthesis.
Images
Immunohistochemistry of paraffin embedded mouse colon using GSK-3A at dilution of 1:2200 (400x lens)
Immunohistochemistry of paraffin embedded mouse epencephalon using GSK-3A at dilution of 1:2200 (400x lens)
Immunohistochemistry of paraffin embedded mouse heart using GSK-3A at dilution of 1:2200 (400x lens)
Immunohistochemistry of paraffin embedded mouse spleen using GSK-3A at dilution of 1:2200 (400x lens)
Immunohistochemistry of paraffin embedded mouse thymus using GSK-3A at dilution of 1:2200 (400x lens)
Immunohistochemistry of paraffin embedded rat brain using GSK-3Aat dilution of 1:2200 (400x lens)
Immunohistochemistry of paraffin embedded rat epencephalon using GSK-3A at dilution of 1:2200 (400x lens)
Immunohistochemistry of paraffin embedded rat spleen using GSK-3A at dilution of 1:2200 (400x lens)
Immunohistochemistry of paraffin embedded rat thymus using GSK-3A at dilution of 1:2200 (400x lens)
Immunofluorescence of paraffin embedded mouse epencephalon using GSK-3Aat dilution of 1:2200 (400x lens)
Immunofluorescence of paraffin embedded mouse heart using GSK-3Aat dilution of 1:2200 (400x lens)
Immunofluorescence of paraffin embedded mouse small intestine using GSK-3A at dilution of 1:2200 (400x lens)
Immunofluorescence of paraffin embedded rat brain using GSK-3A at dilution of 1:2200 (400x lens)
Immunofluorescence of paraffin embedded rat spleen using GSK-3A at dilution of 1:2200 (400x lens)
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.