Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Images
Immunohistochemistry analysis of paraffin-embedded mouse hepatitis using CD68 (GB11067) at dilution of 1: 500
Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD68 (GB11067) at dilution of 1: 500
Immunohistochemistry analysis of paraffin-embedded mouse lung using CD68 (GB11067) at dilution of 1: 500
Immunohistochemistry analysis of paraffin-embedded mouse liver using CD68 (GB11067) at dilution of 1: 500
Immunofluorescent analysis of paraformaldehyde-fixed rat spleen using
CD68 (GB11067) at dilution of 1: 500
Immunofluorescent analysis of paraformaldehyde-fixed mouse bone using CD68(GB11067) at dilution of 1:1000
Immunohistochemistry analysis of paraffin-embedded rat lymph node using CD68(GB11067) at dilution of 1:1000
Immunohistochemistry analysis of paraffin-embedded rat spleen using CD68(GB11067) at dilution of 1:1000
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
Publications:
Title
Journal
Pubmed ID
Application
1
Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophy.
Redox Biology
33152664
IHC
2
Single-cell RNA-Seq reveals the transcriptional landscape and heterogeneity of skin macrophages in Vsir-/- murine psoriasis.
Theranostics
32929361
IHC
3
Anti-Atherosclerosis Effect of Angong Niuhuang Pill via Regulating Th17/Treg Immune Balance and Inhibiting Chronic Inflammatory on ApoE-/- Mice Model of Early and Mid-Term Atherosclerosis.
Frontiers in Pharmacology
32082145
IHC
4
Gaudichaudione H Inhibits Inflammatory Responses in Macrophages and Dextran Sodium Sulfate-Induced Colitis in Mice.
Frontiers in Pharmacology
32009962
IHC
5
Human amnion mesenchymal stem cells attenuate atherosclerosis by modulating macrophage function to reduce immune response.
International Journal of Molecular Medicine
31364743
IHC
6
IL-17A Can Promote Propionibacterium acnes-Induced Sarcoidosis-Like Granulomatosis in Mice.
Frontiers in Immunology
31474992
IHC
7
C1q/TNF-related protein-9 promotes macrophage polarization and improves cardiac dysfunction after myocardial infarction.
Journal of Cellular Physiology
30953351
IF
8
Galectin-3 Mediates Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension.
Aging and Disease
31440380
IHC
9
Carotid baroreceptor stimulation in obese rats affects white and brown adipose tissues differently in metabolic protection.
Journal of Lipid Research
31126973
IHC
10
CXCL12/CXCR4 promotes inflammation-driven colorectal cancer progression through activation of RhoA signaling by sponging miR-133a-3p.
Journal of Experimental & Clinical Cancer Research : CR