Anti -G-CSF Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

DRF101646

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	G-CSF rabbit polyclonal
Protein full name	Granulocyte colony-stimulating factor
Synonyms	G-CSF, Csf3, Csfg, CSF3, GCSA
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse G-CSF
Isotype	IgG
Purity	Affinity purification
Predicted MW.	22 kDa
Observed MW.	19 kDa
Uniprot ID	P09920, P97712

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse, Rat	1: 500-1: 800	kidney, lung, liver

Background

Granulocyte colony-stimulating factor (G-CSF), also referred to as CSF3, is a protective cytokine with anti-inflammatory effects. G-CSF is important in promoting survival of the granulocytic lineage cells and proliferation and migration of neutrophils as well as trophoblast cells. G-CSF acts by binding to its receptor G-CSFR (also called CSF3R), which after binding with G-CSF activates the canonical Janus kinase (Jak)/signal transducer, activator of transcription (STAT)and Ras/Raf/MAP kinase pathways. G-CSF potently stimulates the proliferation and release of peripheral blood progenitor cells into the bloodstream and is therefore used to treat neutropenia after chemotherapy. Furthermore, G-CSF levels are elevated upon intensive exercise leading to increased neutrophil counts, which are predominantly due to delayed neutrophil apoptosis.

Images

Western blot analysis of G-CSF (GB111039) at dilution of 1: 800

Lane 1: Mouse kidney tissue lysate

Lane 2: Mouse lung tissue lysate

Lane 3: Mouse liver tissue lysate

Lane 4: Rat kidney tissue lysate

Lane 5: Rat lung tissue lysate

Lane 6: Rat liver tissue lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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