Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Images
Immunohistochemistry analysis of paraffin-embedded mouse heart using
CD68 (GB113109) at dilution of 1: 400
Immunohistochemistry analysis of paraffin-embedded mouse lung using
CD68 (GB113109) at dilution of 1: 400
Immunohistochemistry analysis of paraffin-embedded rat lung using
CD68 (GB113109) at dilution of 1: 400
Immunohistochemistry analysis of paraffin-embedded rat septic lung using
CD68 (GB113109) at dilution of 1: 400
Immunohistochemistry analysis of paraffin-embedded rat myocardial infarction using CD68 (GB113109) at dilution of 1: 400
Immunofluorescent analysis of paraformaldehyde-fixed mouse hepatitis using CD68 (GB113109) at dilution of 1: 200
Immunofluorescent analysis of paraformaldehyde-fixed mouse immune spleen using CD68 (GB113109) at dilution of 1: 200
Immunofluorescent analysis of paraformaldehyde-fixed mouse lung using
CD68 (GB113109) at dilution of 1: 200
Immunofluorescent analysis of paraformaldehyde-fixed rat pyohemia lung using CD68 (GB113109) at dilution of 1: 200
Immunofluorescent analysis of paraformaldehyde-fixed rat model liver using CD68 with LPS treated for 6h (GB113109) at dilution of 1: 200
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer
PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .