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Anti -CD163 Rabbit pAb

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貨號:
DRF101793
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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Product Information


Description

CD163 rabbit polyclonal

Protein full name

Scavenger receptor cysteine-rich type 1 protein M130

Synonyms

CD163, M130, MM130, SCARI1, CD163

molecule

Immunogen

KLH conjugated Synthetic peptide

corresponding to Human CD163

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membraneSecreted

Uniprot ID

Q86VB7




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human

1: 500-1: 1000

liver cancer, lung, tonsil




Background


Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1.




Images


圖片 1.png

Immunohistochemistry analysis of paraffin-embedded human liver cancer using CD163 (GB113152) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded human lung using 

CD163 (GB113152) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded human tonsil using 

CD163 (GB113152) at dilution of 1: 1000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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