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Anti -Glutamine Synthetase Rabbit pAb

價(jià)格: 在線咨詢
貨號:
KT011497
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
H,M,R
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

Glutamine Synthetase rabbit polyclonal antibody

Protein full name

Glutamine synthetase

Synonyms

Cell proliferation-inducing protein 59, GLNA, GLNS, GLUL,Glutamate ammonia ligase, Glutamate decarboxylase, Glutamine synthetase, GS, PIG43, PIG59,Proliferation inducing protein 43

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Glutamine Synthetase

Isotype

IgG

Purity

Affinity purification

Predicted MW.

42 kDa

Observed MW.

42 kDa

Uniprot ID

P15104, P15105, P09606




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1500

liver, lung, kidney




Background


Glutamine Synthetase catalyzes the conversion of ammonia and glutamate to glutamine. The function of Glutamine Synthetase is the detoxification of brain ammonia. It also has an important role in the metabolic regulation of neurotransmitter glutamate. Because of the multiple functions and importance of Glutamine Synthetase in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of Glutamine Synthetase is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation. The level of expression of Glutamine Synthetase is increased during ischemia in vivo or hypoxia in culture.




Images



Picture 1.png

Western blot analysis of Glutamune synthetase (GB11736) at dilution of 1: 500




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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