kidney cancer, breast cancer, tonsil, thyroid, brain, spleen
IF
Human, Mouse
1: 200-1: 800
brain
Background
NR4A2
belongs to the orphan nuclear receptor (NR) family referred to as NR4A
family, which have been implicated in cell cycle regulation, apoptosis,
inflammation, metabolism and more recently in carcinogenesis . NR4A2
also has a role in the expression of several proteins that are necessary
for the synthesis and regulation of dopamine (DA), such as tyrosine
hidroxilase, dopamine transporter, vesicular monoamine transporter 2 and
cRET [PMID:22294735]. Act as a transcriptional regulator, NR4A2 is
essential for the differentiation and maintenance of meso-diencephalic
dopaminergic (mdDA) neurons during development.
Images
Western blot analysis of Nurr1 (GB111267) at dilution of 1: 800
Lane 1: Jurkat cell lysate
Lane 2: SH-SY5Y cell lysate
Lane 3: HepG2 cell lysate
Lane 4: HT29 cell lysate
Lane 5: Mouse brain tissue lysate
Lane 6: Rat brain tissue lysate
Immunohistochemistry analysis of paraffin-embedded human kidney cancer using Nurr1 (GB111267) at dilution of 1: 800
Immunohistochemistry analysis of paraffin-embedded human breast cancer using Nurr1 (GB111267) at dilution of 1: 200
Immunohistochemistry analysis of paraffin-embedded human tonsil using
Nurr1 (GB111267) at dilution of 1: 400
Immunohistochemistry analysis of paraffin-embedded human thyroid using
Nurr1 (GB111267) at dilution of 1: 200
Immunohistochemistry analysis of paraffin-embedded mouse brain using
Nurr1 (GB111267) at dilution of 1: 800
Immunohistochemistry analysis of paraffin-embedded mouse spleen using
Nurr1 (GB111267) at dilution of 1: 200
Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using
Nurr1 (GB111267) at dilution of 1: 400
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .