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Anti –MRP8 Rabbit pAb

價格: 在線咨詢
貨號:
KT011575
產(chǎn)品規(guī)格:
100ul
Applications:
IHC/IF
Species:
H/M/R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

MRP8 rabbit polyclonal antibody

Protein full name

Protein S100-A8

Synonyms

S100A8, 60B8AG, CAGA, CFAG, CGLA, CP-10, L1Ag, MA387, MIF, MRP8, NIF, P8, S100 calcium

Immunogen

Recombinant protein corresponding to Mouse MRP8

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted, Cytoskeleton, Cell membrane

Uniprot ID

P05109, P27005, P50115




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse, Rat

1:500-1:3000

ovarian cancer, spleen, stomach




Background


S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase.

   



Images



Picture 1.png

Immunohistochemistry of paraffin embedded mouse spleen using S100A8 (GB11421) at dilution of 1:1500 (400x lens)

Picture 2.png

Immunohistochemistry of paraffin embedded rat spleen using S100A8 (GB11421) at dilution of 1:1500 (400x lens)

Picture 3.png Immunofluorescence of paraffin embedded human ovarian cancer using S100A8 (GB11421) at dilution of 1:1500 (400x lens)
Picture 4.png

Immunofluorescence of paraffin embedded mouse spleen using S100A8 (GB11421) at dilution of 1:1500 (400x lens)

Picture 5.png

Immunofluorescence of paraffin embedded rat stomach using S100A8 (GB11421) at dilution of 1:1500 (400x lens)




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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