Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Images
Immunohistochemistry of paraffin embedded mouse brain using IBA-1 (GB12105) at dilution of 1: 2000 (300x lens)
Immunohistochemistry of paraffin embedded rat brain using IBA-1 (GB12105) at dilution of 1: 2000 (300x lens)
Immunohistochemistry of paraffin embedded rat brain using IBA-1 (GB12105) at dilution of 1: 2000 (300x lens)
Immunofluorescent analysis of paraffin embedded rat hippocampus using Neun (GB11138) (green) + Iba1 (GB12105) (red) + MBP (GB12226) (spred) + GFAP (GB11096) (yellow) and Dapi in blue at dilution of 1: 1000
Immunofluorescence of paraffin embedded mouse brain using IBA-1 (GB12105) at dilution of 1: 1000 (200x lens)
Immunofluorescent analysis of paraffin embedded rat brain using Neun (GB11138) (green)+ Iba1 (GB12105) (spred) + MAP2 (GB11128-2) (red) and Dapi in blue at dilution of 1: 1000
Immunofluorescence of paraffin embedded rat brain using IBA-1 (GB12105) at dilution of 1: 1000 (400x lens)
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .