Anti -CollagenI Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

KT011823

產(chǎn)品規(guī)格：

100ul

Applications：

WB/IHC/IF

Species：

H/M/R,H/M/R,H/M/R

品牌：

萬物

購買數(shù)量：

立即詢價(jià) 在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	Collagen I rabbit polyclonal
Protein full name	Collagen alpha-1(I) chain
Synonyms	COL1A1, EDSC, OI1, OI2, OI3, OI4, collagen type I alpha 1, collagen type I alpha 1 chain
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse COL1A1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	138 kDa
Observed MW.	120 kDa
Uniprot ID	P02452, P11087, P02454

Applications

applications	species	dilution	Positive tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	skin, uterus, lung, cartilage
IHC	Human, Mouse, Rat	1: 200-1: 1700	lung, skin
IF	Human, Mouse, Rat	1: 100-1: 1000	lung, skin

Background

This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.

Images

	Western blot analysis of Collagen I (GB11022) at dilution of 1: 2000 Lane 1: MCF-7 cell lysate Lane 2: Mouse cartilage tissue lysate Lane 3: Mouse skin tissue lysate Lane 4: Mouse uterus tissue lysate Lane 5: Rat cartilage tissue lysate Lane 6: Rat lung tissue lysate Lane 7: Rat skin tissue lysate
	Immunohistochemistry analysis of paraffin-embedded mouse lung using Collagen I (GB11022) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded rat lung using Collagen I (GB11022) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded rat skin using Collagen I (GB11022) at dilution of 1: 2000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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