Anti -Cyclin D1 Rabbit pAb

價格：在線咨詢

貨號：

KT011855

產(chǎn)品規(guī)格：

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	Cyclin D1 rabbit polyclonal antibody
Protein full name	G1/S-specific cyclin-D1
Synonyms	Ccnd1, Cyl-1, B-cell lymphoma 1 protein, BCL-1, Parathyroid adenomatosis 1, PRAD1, BCL1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse Cyclin D1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	33 kDa
Observed MW.	33 kDa
Uniprot ID	P24385, P25322, P39948

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse, Rat	1: 500-1: 1000	MCF-7, A431, SH-SY5Y, THP-1, L929, RAW 264.7, C6, PC-12

Background

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb.

Images

Western blot analysis of cyclinD1 (GB111935) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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