Cyclin
E1 (CCNE1) is a member of the highly conserved cyclin family, whose
members are characterized by a dramatic periodicity in protein abundance
through the cell cycle. CCNE1, an essential cyclin activating Cdk2,
regulates the G1-S phase transition of the mammalian cell division
cycle. Its timing expression plays a direct role in the initiation of
DNA replication , the control of histone biosynthesis, and the
centrosome cycle. CCNE1 is associated with disease progression in
various malignancies and is associated clinically with poor prognosis.
Images
Western blot analysis of Cyclin E1
at dilution of 1: 500
Lane 1: HeLa cell lysate
Lane 2: MCF7 cell lysate
Lane 3: K562 cell lysate
Lane 4: Mouse testis tissue lysate
Lane 5: Mouse colon tissue lysate
Lane 6: Mouse placenta tissue lysate
Lane 7: Rat testis tissue lysate
Lane 8: Rat colon tissue lysate
Lane 9: Rat placenta tissue lysate
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer
PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .