Anti -Beclin 1 Rabbit pAb

價格：在線咨詢

貨號：

KT012180

產品規(guī)格：

100 μL

Applications：

Species：

H,M,R

品牌：

萬物

購買數量：

立即詢價在線咨詢 400-1016-218

產品詳情操作說明注意事項

Product Information

Description	Beclin 1 rabbit polyclonal antibody
Protein full name	Beclin-1
Synonyms	Coiled-coil myosin-like BCL2-interacting protein, Protein GT197, BECN1, GT197, APG6, VPS30, Protein GT197
Immunogen	KLH conjugated Synthetic peptide corresponding to Human Beclin 1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	52 kDa
Observed MW.	60 kDa
Uniprot ID	Q14457, O88597, Q91XJ1

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	brain, spleen, kidney

Background

Beclin 1 is the first identified mammalian gene to mediate autophagy and also has tumor suppressor and antiviral function. Autophagy, a process of bulk protein degradation through an autophagosomic lysosomal pathway, is important for differentiation, survival during nutrient deprivation, and normal growth control, and is often defective in tumor cells. Beclin 1 was originally isolated in a yeast two hybrid screen to identify Bcl 2 binding partners and maps to a tumor susceptibility locus on human chromosome 17q21 that is frequently monoallelically deleted in human breast, ovarian and prostate cancer. Beclin 1 encodes an evolutionarily conserved 52kDa coiled coil protein that is expressed in human muscle, epithelial cells and neurons.

Images

Picture 1.png

Western blot analysis of Beclin1 (GB112053) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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