Anti -Beclin 1 Rabbit pAb

價格：在線咨詢

貨號：

KT012182

產品規(guī)格：

100 μL

Applications：

IHC/IF

Species：

H,M

品牌：

萬物

購買數量：

立即詢價在線咨詢 400-1016-218

產品詳情操作說明注意事項

Product Information

Description	Beclin1 rabbit polyclonal antibody
Protein full name	Beclin-1
Synonyms	BECN1, ATG6, NVPS30, beclin1, beclin-1, GT197
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse Beclin1
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm, Nucleus
Uniprot ID	Q14457

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Human, Mouse	1: 500-1: 4000	kidney

Background

Plays a central role in autophagy . Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 . Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms.

Images

Picture 1.png

Immunofluorescence of paraffin embedded mouse kidney using Beclin1 (GB11228) at dilution of 1:2200 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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