Anti -XIAP Rabbit pAb

價格：在線咨詢

貨號：

KT012195

產(chǎn)品規(guī)格：

100ul

Applications：

Species：

H/M

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	XIAP rabbit polyclonal antibody
Protein full name	E3 ubiquitin-protein ligase XIAP
Synonyms	Baculoviral IAP repeat-containing protein 4, IAP-like protein, API3, BIRC4, IAP3, XIAP, ILP, hILP, Inhibitor of apoptosis protein 3, IAP-3, hIAP3, X-linked IAP
Immunogen	Recombinant protein corresponding to Mouse XIAP
Isotype	IgG
Purity	Affinity purification
Predicted MW.	57 kDa
Observed MW.	57 kDa
Uniprot ID	P98170, Q60989

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse	1: 500-1: 1000	MCF-7, HT-29, Jurkat, Raji, PC-12, HepG2

Background

XIAP, also named as API3, BIRC4 and IAP3, belongs to the IAP family. It has E3 ubiquitin-protein ligase activity. It mediates the proteasomal degradation of target proteins, such as caspase-3, SMAC or AIFM1. XIAP is an inhibitor of caspase-3, -7 and -9. It mediates activation of MAP3K7/TAK1, leading to the activation of NF-kappa-B. XIAP is an apoptotic suppressor. It is ubiquitinated and degraded by the proteasome in apoptotic cells.

Images

Picture 1.png

Western blot analysis of XIAP (GB111208) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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