Anti -Mannose Receptor Rabbit pAb

價格：在線咨詢

貨號：

DRF101797

產品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產品詳情操作說明注意事項

Product Information

Description	Mannose Receptor rabbit polyclonal
Protein full name	Macrophage mannose receptor 1
Synonyms	CD206, CLEC13D, Macrophage mannose receptor 1, Mannose receptor, mannose receptor, C type 1, MMR, MRC1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse Mannose Receptor
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane, Endosome
Uniprot ID	Q61830

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Mouse	1: 400-1: 800	lung
IF	Mouse	1: 400-1: 800	lung

Background

CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane glycoprotein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail.

Images

Immunohistochemistry analysis of paraffin-embedded mouse lung with LPS treated for 24h using CD206 (GB113497) at dilution of 1: 800

圖片 2.png

Immunofluorescent analysis of paraformaldehyde-fixed mouse lung with LPS treated for 24h using CD206 (GB113497) at dilution of 1: 800

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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