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Anti -GABA A Receptor alpha 1 Rabbit pAb

價格: 在線咨詢
貨號:
KT011491
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
H
購買數(shù)量:
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Product Information


Description

GABA A Receptor alpha 1 rabbit polyclonal antibody

Protein full name

Gamma-aminobutyric acid receptor subunit alpha-1

Synonyms

GABRA1, ECA4, EIEE19, EJM, EJM5, Gamma-aminobutyric acid type A receptor alpha1 subunit

Immunogen

Recombinant protein corresponding to Mouse GABA A Receptor alpha 1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

52 kDa

Observed MW.

52 kDa

Uniprot ID

P14867




Applications


Applications

Species

Dilution

Positive Sample

WB

Human

1: 500-1: 1000

U87, U251, SH-SY5Y




Background


Gamma-aminobutyric acid receptor subunit alpha-1 is a protein that in humans is encoded by the GABRA1 gene. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. The GABRA1 receptor is the specific target of the z-drug class of nonbenzodiazepine hypnotic agents and is responsible for their hypnotic and hallucinogenic effects.




Images



Picture 1.png

Western blot analysis of GABAARα1 (GB11561) at dilution of 1: 500




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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