Anti -CLIP170 Rabbit pAb

價格：在線咨詢

貨號：

KT011856

產品規(guī)格：

100ul

Applications：

Species：

H/M/R

品牌：

萬物

購買數量：

立即詢價在線咨詢 400-1016-218

產品詳情操作說明注意事項

Product Information

Description	CLIP170 rabbit polyclonal antibody
Protein full name	CAP-Gly domain-containing linker protein 1
Synonyms	Cytoplasmic linker protein 170, CLIP-170, Restin, Clip1, Kiaa4046, Rsn
Immunogen	Recombinant protein corresponding to Mouse CLIP170
Isotype	IgG
Purity	Affinity purification
Predicted MW.	162 kDa
Observed MW.	180 kDa
Uniprot ID	P30622, Q922J3, Q9JK25

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	brain

Background

CLIP170 was initially identified as a new type of intermediate filament associated protein that is highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin's disease. Later experiments showed that it is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles. CLIP170 has also been suggested to act with LIS1, a protein implicated in brain development, to regulate dynein dynactin binding microtubules. Other studies suggest that CLIP170 can influence the formation of lamellipodia and cell invasion by invasive breast cancer cells by regulating the release of kinesin and IQGAP1 from a complex of those proteins, CLIP170 and Rac1.

Images

Picture 1.png

Western blot analysis of clip (GB111068) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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