Anti -Myosin light chain 3 Rabbit pAb

價格：在線咨詢

貨號：

KT011885

產(chǎn)品規(guī)格：

100ul

Applications：

WB/IHC/IF

Species：

M/R,M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	Myosin light chain 3 rabbit polyclonal antibody
Protein full name	Myosin light chain 3
Synonyms	Myosin alkali light chain 1, ventricular/slow skeletal muscle isoform, MLC1SB, Myl3, Mlc1v, Mylc, Myosin light chain 3
Immunogen	Recombinant protein corresponding to Mouse Myosin light chain 3
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm
Predicted MW.	22 kDa
Observed MW.	23 kDa
Uniprot ID	P09542, P16409

Applications

Applications	Species	Dilution	Positive Sample
WB	Mouse, Rat	1: 500-1: 1000	heart, skeletal muscle
IHC/IF	Mouse, Rat	1: 1500-1: 3000	esophagus, lung, Skeletal muscle

Background

MYL3, also named as MLC1v, is an essential light chain of myosin that is associated with muscle contraction. It is expressed in ventricular and slow skeletal muscle. MYL3 may serve as a target for caspase-3 in dying cardiomyocytes. Mutations of MYL3 gene cause hypertrophic cardiomyopathy. MYL3 has been identified as potential serum biomarker for drug induced myotoxicity. Great increase in MYL3 serum concentration has been observed in rats with cardiac and skeletal muscle injury.

Images

	Western blot analysis of MYL3 (GB111241) at dilution of 1: 500
	Immunohistochemistry of paraffin embedded mouse lung using MYL3 (GB111241) at dilution of 1: 3400 (400x lens)
	Immunohistochemistry of paraffin embedded mouse skeletal muscle using MYL3 (GB111241) at dilution of 1: 1700 (400x lens)
	Immunohistochemistry of paraffin embedded rat esophagus using MYL3 (GB111241) at dilution of 1: 3400 (400x lens)
	Immunohistochemistry of paraffin embedded rat skeletal muscle using MYL3 (GB111241) at dilution of 1: 1700 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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