PPIase A, Cyclophilin A, Ppia, Cyclosporin A-binding protein, Rotamase A, SP18
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Cyclophilin A
Isotype
IgG
Purity
Affinity purification
Predicted MW.
18 kDa
Observed MW.
18 kDa
Uniprot ID
P62937, P17742, P10111
Applications
Applications
Species
Dilution
Positive Sample
WB
Human, Mouse, Rat
1: 500-1: 1000
heart, brain, thymus
Background
Cyclophilin A, also named as PPIA and Rotamase A, belongs to the cyclophilin-type PPIase family and PPIase A subfamily. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity. PPIA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication.
Images
Western blot analysis of cyclophilin-A (GB111283) at dilution of 1: 500
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).