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Anti -Topoisomerase II alpha Rabbit pAb

價格: 在線咨詢
貨號:
KT012096
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
MR
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

Topoisomerase II alpha rabbit polyclonal antibody

Protein full name

DNA topoisomerase 2-alpha

Synonyms

DNA topoisomerase II, alpha isozyme, TOP2A, Top-2, Top2

Immunogen

Recombinant protein corresponding to Mouse Top2a

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Uniprot ID

Q01320, P41516




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Mouse, Rat

1: 500-1: 2000

brain, ovary, thymus, thymus+LPS




Background


This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event.




Images


Picture 1.png Immunohistochemistry of paraffin embedded mouse brain using Top2 (GB111031) at dilution of 1:600 (400x lens)
Picture 2.png Immunohistochemistry of paraffin embedded mouse ovary using Top2 (GB111031) at dilution of 1:5000 (400x lens)
Picture 3.png Immunohistochemistry of paraffin embedded mouse ovary using Top2 (GB111031) at dilution of 1:600 (400x lens)
Picture 4.png Immunohistochemistry of paraffin embedded mouse thymus using Top2 (GB111031) at dilution of 1:5000 (400x lens)
Picture 5.png Immunohistochemistry of paraffin embedded mouse thymus using Top2 (GB111031) at dilution of 1:600 (400x lens)
Picture 6.png Immunohistochemistry of paraffin embedded rat brain using Top2 (GB111031) at dilution of 1:600 (400x lens)
Picture 7.png Immunohistochemistry of paraffin embedded rat ovary using Top2 (GB111031) at dilution of 1:5000 (400x lens)
Picture 8.png Immunohistochemistry of paraffin embedded rat ovary using Top2 (GB111031) at dilution of 1:600 (400x lens)

Picture 9.png

Immunohistochemistry of paraffin embedded rat thymus+LPS using Top2 (GB111031) at dilution of 1:5000 (400x lens)

Picture 10.png

Immunohistochemistry of paraffin embedded rat thymus+LPS using Top2 (GB111031) at dilution of 1:600 (400x lens)

Picture 11.png

Immunofluorescence of paraffin embedded mouse ovary using Top2 (GB111031) at dilution of 1:500 (400x lens)

Picture 12.png

Immunofluorescence of paraffin embedded rat thymus using Top2 (GB111031) at dilution of 1:500 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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