Anti -TDP1 Rabbit pAb

價格：在線咨詢

貨號：

KT012108

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	TDP1 rabbit polyclonal antibody
Protein full name	Tyrosyl-DNA phosphodiesterase 1
Synonyms	Tyr-DNA phosphodiesterase 1, Protein expressed in male leptotene and zygotene spermatocytes 501, MLZ-501, Tdp1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse TDP1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	69 kDa
Observed MW.	69 kDa
Uniprot ID	Q8BJ37, Q4G056

Applications

Applications	Species	Dilution	Positive Sample
WB	Mouse, Rat	1: 500-1: 1000	stomach, liver, kidney

Background

The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1).

Images

Picture 1.png

Western blot analysis of TDP1 (GB111302) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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