DNA topoisomerase II, alpha isozyme, TOP2A, Top-2, Top2
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse TOP2A
Isotype
IgG
Purity
Affinity purification
Subcellular location
Cytoplasm, Nucleus
Uniprot ID
P11388, Q01320, P41516
Applications
Applications
Species
Dilution
Positive Sample
IHC/IF
Human, Mouse, Rat
1: 1500-1: 3000
brain, breast cancer, colon, placenta, testis, thymus
Background
TOP2A, also named as TOP2, belongs to the type II topoisomerase family. Topoisomerase II makes double-strand breaks. TOP2 control the topological states of DNA by transient breakage and subsequent rejoining of DNA strands.
Images
Immunohistochemistry of paraffin embedded human breast cancer using TOP2A (GB111293) at dilution of 1:1400 (400x lens)
Immunohistochemistry of paraffin embedded mouse colon using TOP2A (GB111293) at dilution of 1:1400 (400x lens)
Immunohistochemistry of paraffin embedded mouse placenta using TOP2A (GB111293) at dilution of 1:1400 (400x lens)
Immunohistochemistry of paraffin embedded mouse testis using TOP2A (GB111293) at dilution of 1:1400 (400x lens)
Immunohistochemistry of paraffin embedded rat colon using TOP2A (GB111293) at dilution of 1:1400 (400x lens)
Immunohistochemistry of paraffin embedded rat placenta using TOP2A (GB111293) at dilution of 1:1400 (400x lens)
Immunofluorescence of paraffin embedded human colon using TOP2A (GB111293) at dilution of 1:1400 (400x lens)
Immunofluorescence of paraffin embedded mouse brain using TOP2A (GB111293) at dilution of 1:1400 (400x lens)
Immunofluorescence of paraffin embedded mouse testis using TOP2A (GB111293) at dilution of 1:1400 (400x lens)
Immunofluorescence of paraffin embedded rat thymus using TOP2A (GB111293) at dilution of 1:1400 (400x lens)
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).